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Trials designed to inform clinical practice in the real world are referred to as pragmatic trials. They are typically characterized by a focus on the practical aspects of study design, such as the recruitment and consent process as well as adherence to the use of commonly available equipment.
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Pragmatic Software, a software firm provides a variety of casino games to online gambling platforms. Its iGaming software is used by top operators as well as land-based casinos. The company offers front-end site design tools, analysis tools and marketing, promotions security, payment systems, customer support and bug-reporting. In addition, the company provides its players a safe and secure environment that features high-quality graphics and gaming.
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RTP
Pragmatic Play, one of the most popular iGaming firms offers a wide selection of slot games. Certain games have high RTPs which allow players to maximize their chances of winning. Many of the games from the company also have mobile compatibility, making them ideal for playing on tablets and smartphones. Some of these games even have an extra game that allows players to win free spins.
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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and participants from different geographical regions. This type of heterogeneity, that is crucial for pragmatic trials to be valid and reduce bias in results, is also necessary. However too much heterogeneity could lead to problems with the design of the trial.
Pragmatic Play is one of the biggest players on the live casino market, provides an array of traditional table games like Blackjack and Roulette. The live studios of Pragmatic Play in Romania and Malta offer customers an authentic experience in gambling as well as a broad selection of virtual betting options. The company also offers a variety of game shows that make online gambling more enjoyable and engaging. Some of these shows are broadcast live, while others include famous people from the industry.
Mobile compatibility
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Legality
Pragmatic Play has gained a reputation for offering high-quality games and a superior user experience. Its software is designed to work on mobile devices and supports various languages. It has earned itself the status of one of the top casino gaming platforms despite its relatively young age. The most recent releases include Wolves 5 reel video slot with a healthy RTP and stunning graphics. Other notable titles include Wolf Gold and Chilli Heat.
The goal of pragmatic trials is to mimic real-life scenarios and to achieve the highest level of validity externally. They are usually commissioned by policymakers and practitioners in order to guide their decisions. They are also a good method to determine the causality between the intervention and its effects. They should not, however, be used to replace the need for explanation studies.
The concept of pragmatism is controversial, and there are concerns about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which confirm the validity of a physiological or clinical hypothesis, and pragmatic trials, that inform the practice and policy decision-making. They also proposed a framework for pragmatic trials, dubbed PRECIS.2 This tool attempted to define the features of a practical trial, including recruitment, design and delivery of the intervention, as well as monitoring.
There is an encouraging trend in the number of pragmatic trials that have been published. A recent Medline search using the terms naturalistic and pragmatic, limited to controlled trials randomized to control (RCTs), yielded 34 articles, which are shown in red in Figure 2. This is a sign that the health sciences community is becoming more sensitive to the issue of pragmatic thinking. It is important to note that the majority of these studies were conducted in primary care settings.